SBS新水木剧《SIGN》2011年01月05日首播， 每周三四晚北京时间21点05分各播放一集，《sign》将以韩国国立科学搜查研究所为舞台，述说在国立科学搜查研究所所发生的法医们的苦痛和生活，还有围绕在他们当中的疑问事件的医学搜查物，破解各种疑案的过程，案件背后隐藏的真相以及组织内部的明争暗斗的故事。
男主角尹志勋（朴新阳饰）是韩国最佳法医学者，虽然有著理智的外貌并获得世界肯定的实力者,但却是有著奇特个性的国立科学搜查研究所法医.是个有著多样个性的人物.该角色原本兼具知性和理智，却因贪欲而陷入了自我矛盾当中。
女主角高多景（金雅中饰）虽然每天照三餐似的被挑剔完美主义者前辈尹志勋（朴新阳饰）斥责，实则是个外柔内刚非常执著的女验尸官，高多景因遇上性格乖僻的前辈而天天挨刺儿，但是凭借乐观向上的精神坚持了下来，最终为破获一起大案立下了汗马功劳。
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