何丽珠与才俊丈夫认识七天后结婚，丈夫因意外去世，珠成有钱寡妇。一次意外后，她发现自己左眼可以看见鬼。声称是何丽珠小学同学的顽皮鬼王劲威找上了她，使她多行善事。日子越长，一人一鬼建立起真挚友谊。王劲威快要投胎，何丽珠要求见老公一面... 何丽珠（郑秀文饰）遇到了一个英俊、博学又很有钱的完美男人，他们相识7天之后就闪电结婚，但丈夫却在婚后不久便去世，于是何丽珠成了富有的寡妇。丈夫的去世使得何丽珠情绪低落，养成了很多缺点。她酗酒、抽烟，说话尖酸刻薄等等，身为公司董事，还经常找借口不上班。这天，何丽珠又随口以自己右眼视网膜脱落为借口请假，当她用纱布敷住右眼走在路上时遇到有人跳楼自杀，然后她发现自己的左眼有特异功能，能看到鬼。各路游魂得知她有这一功能后，纷纷找上门来请她帮忙实现未了的心愿。这些鬼中以王劲威（刘青云饰）最烦人，但相处多日后何丽珠竟对他产生了好感。一日，何丽珠突发奇想，要青云帮他寻找在阴间的丈夫，但王劲威却没有找到，何丽珠因此责怪丈夫狠心地丢下自己早早投胎，于是她也决定重新做人。再后来她的特异功能消失了，却发现家中处处都留下了王劲威的痕迹，一切仿佛当年结婚时的样子，原来王劲威就是她丈夫的影子.
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