杜佳期本来是民初一间大药厂的千金小姐，谁知药厂有问题令她家道中落，加上发生好多疫症，为了挽救民众的生命，她想尽一切方法治病救人。以前的女人是不能做药师的，对于种种岐视她都坚强面对终于成长为一位优秀的药师。
一元与洪炳、皇甫寿及金福到了毒源所在的水井，一元因绳断了跌进毒水裏，更不顾危险把毒素瓶拾回。锡庚与杜蔘对毒症无从入手，锡庚气言除非用五个病人试药，或可找到救治方法，但其中四人会死去。中毒的一元被擡回尚春堂，佳期誓要医好一元。佳期准备五碗汤药，欲以身试毒；在昏迷醒来後，终找到解毒方法。解毒药丹终於炼制…
魏俊在椅底取回浓缩毒素，欲杀敦儒与秀梅，继宗折返及时阻止，君约看见魏俊的枪指向继宗头部，突然清醒扑向前，推开魏俊的手，魏俊的枪被踢开，立即逃走。杜茸到了码头，向赌坊的阿茂取了卖玉琴的一百大洋後，藉口给玉琴买零吃，便抛下玉琴走了。佳期与一元等到码头找玉琴及杜茸，发现杜茸踪影。玉琴被催促上船，才知道杜茸…
杜茸重提想玉琴把胎打掉，玉琴坚拒，她提议找个地方躲起来把孩子生下，二人惊见佳期与杜蔘回家。玉琴依旧服侍杜蔘，杜蔘却著她留在房间睡，他则到客房去。佳期问父为何会这样，杜蔘自问年纪大玉琴那麼多，娶她作填房是难为了她。崇明告知魏俊，南京政府已知悉他所做的一切，云南的兵工厂已被捣破，他的军队被收回，有毒武器…
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