影片讲述了一个怀孕的AV女星，两个不走运的应召女郎，一个狂迷哥特的小女孩，以及一个狂恋上名人的空姐等八个不尽相同的女人的故事，虽然身份不尽相同，但是有一点相通：她们都陷入了麻烦之中。意外事见，既是挑战也是惊喜，且看这些女人如何应对。 当se情明星埃莱克特拉（卡拉·古奇诺饰）发现自己怀有身孕后，她狂放不羁的生活方式一下子被打乱了。紧接着，她和精神病患者多丽丝（康妮·布里登饰）一同被困在电梯里，在此情此景之下，莱克特拉一瞬间联想起自己的现状，明白到自己目前正处于人生的十字路口中。与此同时，成人电影最新的后起之秀霍利（阿德琳妮·帕里奇饰）与她性感的女友班比（埃曼纽尔·施莱琪饰）争吵得不可开交，因为班比不愿意将她们俩的同性关系放在屏幕上作真人秀。另一方面，精神学医师（莎拉·克拉克饰）发现自己的丈夫不忠；空姐（玛丽·谢尔顿饰）疯狂地迷恋上自己的乘客——一名高级俱乐部里的名人；早熟的花季少女（伊莎贝拉古·铁雷斯）突然意识到大人们总是按着自己的意愿去摆布她，这让她不堪其烦。有一晚，阿德琳妮所扮演的霍莉与埃曼纽尔·施莱琪所扮演的班比异想天开地想扮演一回《修女也疯狂》，然而，一切并没能按计划进行，“麻烦事”总是会不请自来……
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