本片改编自爱伦·坡短篇小说《塔尔博士和费瑟尔教授的疗法》（The System of Doctor Tarr and Professor Fether），讲述一个精神病院医生爱上了美丽的女病患的故事。故事中，一位哈佛医科毕业的学生来到一家精神病院就职，最开始他并没有发现任何异常，但随着时间的推移他却逐渐注意到医院已经被那些歇斯底里的病人们所控制，医生护士都成为了可怜的牺牲品。
《地狱病院》演出阵容强大，除了贝金赛尔，还有两大戏骨迈克尔·凯恩、本·金斯利助阵，当红男星吉姆·斯特吉斯、“卢平教授”大卫·休里斯、“疯眼汉”布莱丹·格里森也在麾下。影片由Sobini Films和梅尔·吉普森的电影公司共同制作，首款预告片将于近日发布，预定2014年北美上映。
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